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You don’t have any single non-degraded copy but you do have billions of degraded copies. Assuming errors are non-correlated, one ought to be able to reconstruct the original sequence given enough of them.

The idea would be to use some far-future technology to enable a kind of DNA repair that cells themselves can’t do, using non-local information from other cells in the organism.

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Most mutations are probably large scale chromosomal missegregation, etc where huge chunks get moved around or duplicated/deleted rather than just replacing/removing/adding a single nucleotide. From what I have read something like that happens about once every 10 divisions per cell line.

So I think that could be more difficult than you expect.

I think the same statistical methods apply to cancel the noise.

I doubt it, it isn't like the average is going to correspond to the actual original sequence.

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