www.passwordless.dev has a demo passwordless fido2 login workflow that will trigger the fido2 pin prompt in Chrome.
‡ Referring to "Go usernameless too" which is the mode where a PIN is needed. All the other modes are just plain FIDO and don't need any further verification, and they work just fine on all my systems with any of my tokens.
Using the FIDO2 Yubikey as sole source of truth replacing usernames and passwords is not available in U2F that's a WebAuthn feature only and apparently it doesn't work in Firefox yet which is disappointing.