It's actually easier to support this in Linux than a "conventional" PIN-based FIDO2 token because the Linux system doesn't need to arrange to read a PIN from the user and send that to the token, the token is going to read the user's fingerprint instead.
If you just want a second factor, it'll work like an old FIDO device, which you might be familiar with for U2F - everything is already in place, loads of people are doing this including with Yubico's existing FIDO2 (pin-based) product.
If you want this to be the sole factor (as in the Windows demos or for a site where the convenience of one touch login is good but you don't need MFA security) that ought to work with WebAuthn out of the box, but I actually haven't seen a demo, so I can't say this from personal experience even though I own a FIDO2 token.