At the university of Antwerp they gave Oberon as the first programming language for Computer Science (back in 1997). The reasoning of the professor was so that everyone started from scratch, because nobody would know it already.
It was indeed an eye opener on how many different things there can still be. Especially the mouse key combinations that you had to press were pretty unique.
Never used it ever since that first year, but it's hard to forget because it was so different.