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Comment by rictic | Hacker News Reader

Part of the answer is that mammals are three to seven orders of magnitude larger than amoeba. That comes with some advantages! Immune systems are super complicated, and can leverage the resources of a vast cooperating superorganism of cells.

That sort of thing has happened before though. Oxygen was originally a pollutant that caused the extinction of most species on the planet. This is sometimes called the Oxygen Holocaust (more commonly, the Great Oxidation Event https://en.wikipedia.org/wiki/Great_Oxidation_Event).

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Its not a great answer because despite superior size and having immune systems, microbial life is still routinely deadly, just not too often so deadly to cause extinctions. I have read microbiologists puzzles over for example, what mechanisms 'evolves' strains of flu viruses between periods of relative dormancy and deadly flare up.

That oxidation event represents one major collapse on an ancient scale, but did not owe to a species over-predating others, which Im considering here as a more pervasive risk for species 'dynamics' than pollution/poisoning.

I find no firm answer to these concerns. We dont know that species genetic information has not evolved to avoid over-competitiveness, configurations that could be broken by non-evolved modifications, mass reproductions and releases into the system. Its not a matter which can be settled by current insights, so its somewhat plausibly disguarded as fear and uncertainty. But it might even be the case that what genetics may naturally evolve are naturally confined to modest competitiveness by a property of the yet mysterious steps which enable life to evolve - because we don't even know in what circumstance life evolves. Plenty of theories but no one has ever observed life assembling and evolving from lifelessness, or even modelled a viable sequence illustrating it, and not from lacking of trying for the great achievement and accolades that would bring. Its such an amazing scientific subject, the developed science is amazing too but not nearly so much as its subject matter - biological complexity and remaining mysteries. Its worth treating with special care and humility of some kind.

The fact that we can’t explain the exact steps from stones to microorganisms is no reason to start showing “humility” to intelligent design - agnostic respect to that idea on an equal footing to all others is more than sufficient.

The prospect of intelligent creators is irrelevant here as if they are present they are unseen. What can be partially made out is the broad path of evolution which has actually somehow arrived by its own properties on intelligence in animals - and also appearances of intelligent/cooperative etc. relationships between species. Many different kinds of relationships over kinds of chemistry and activity are present, which themselves may evolve and may have evolved over and throughout species.

The presumptive outlook is that all of the simple and complex evolutionary processes are in sum and product - assuredly mundane, stochastic, resilient to any accidental discord which could be caused by humans bodging their evolved configurations and then non-competitively reproducing trillions of carriers and spreading and maintaining them across the globe with no means to ever recall the version. That's GM agriculture described 'on an equal footing' with the products of natural history.

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