Google Maps tells me this is a 14 minute drive (old HQ to Oyster Point Park). 16-30 minutes if you want to arrive at 8am. Is that correct? Is that such a game changer? Do that many people not own vehicles or can't carpool to work?
From Oakland/the East Bay, there is no good way to get to South San Francisco by public transportation. You are looking at a 2+ hour commute in each direction to go < 15 miles
Is the ferry considered public transportation? I don't live in the area at all, so I'm just poking around on Google Maps to see what the situation is like, so I'm geniuingly asking.
Of course, if you do a driving estimate outside of commute hours, it won't match a commute time estimate, in many places.