It's fantastic especially for general purpose work and browsing, browsing is so much more easier with the SlimBlade, turning the ball to scroll.
The only time I find a mouse more efficient is if doing lots of selecting text and copy/pasting or diagram type apps. I have a backup mouse for when a mouse is more useful but almost never use it.
I was getting minor RSI which is why I originally thought i'd try a trackball. Glad I got one, it's so much more comfortable and wrists / arms now stay relativity still. It's just a shame the form factor isn't that great for carrying about with a laptop.
I'm using it for ~2 years now, before I had the expert mouse for about 10 and before some PS2 trackball. The Slimblade is by far the best - both ergonomically and and mechanically. (previous trackballs tend to collect a lot of dirt and required frequent cleaning, this one have a hole beneath the ball that prevents accumulation)
On my couch / entertainment computer I use a Logitech M570, but for work nothing beats the Slimblade.
I'd actually love a laptop with a trackball instead of a trackpad, but nobody mainstream makes those.
I am rocking CST2545W(GL) BLUE[1] now-a-days. With plenty of other track balls you can see over on r/trackballs[2].
[0] https://www.logitech.com/en-us/product/wireless-trackball-m5...
I use a keyboard for most interaction (XMonad, vim shortcuts in most apps) so YMMV, but really enjoying it so far. The weighting is beautiful, there's four map-able buttons, but the nicest element is a ring that sits around the ball. Spinning it in each direction acts as a scroll and is one of nicest feeling inputs I've used.
My only complaint is that the trackball (on the M570) should be 2X it's current diameter, I don't know why they make them so small.
My mice have thumb trackballs: my fingers stay on the mouse buttons while I use my thumb to scroll, so I don't need to lift them to move the mouse pointer.
That means your wrist sees less strain + motion, and you have no need for a mouse-pad, to name two possible benefits. Some people find it to be more precise as well, but I don't know if there's any evidence apart from personal preference.
Of course, your wrist still moves some as you manipulate the ball with your fingers, and if you use a trackpad you already don't need a mousepad-like-surface.
On CAD applications is very annoying when the mouse unintentionally register a movement while clicking a button which never happens with a trackball.
Well, for me it is much more precise. Or at least seems more natural.
But... ergonomic warning... I switch up between three different trackballs to keep “trackball thumb” from setting in. I get pain in the base joint if I don’t vary the angle, and also spend some time using a finger-positioned trackball.
My first four years out of college I spent a lot of time in that space, so I got quite comfortable with trackballs. Now I use them exclusively on my desktop. My only complaint is they aren't embedded flush in the desktop :)
I also got my SO and her parents to switch. My SO plays games a lot and had started getting problems around her wrist. She never came back to the mouse.
It's fantastic.
My hands are too big for most normal mice; trackballs are just way more comfortable for me.