A carnivorous diet (meat only, zero carbs) would accomplish the same without the pharmacological drawback. Been on the diet for over a year and have never felt better in my life.
This medication is intended to block glucose transport to cancer cells while not blocking to non-cancer cells. Even if a zero carb diet would be a good idea for a cancer patient in general, there is absolutely no chance that a zero carb diet would be equivalent to the intended mechanism of this medication because people with a zero carb diet still have plenty of glucose.
> In fact, the late George Cahill did an experiment many years ago (probably would never get IRB approval to do such an experiment today) to demonstrate how ketones can offset glucose in the brain. Subjects with very high levels of B-OHB (about 5-7 mM) were injected with insulin until glucose levels reached 1 mM (about 19 mg/dL)! A normal person would fall into a coma at glucose levels below about 40 mg/dL and die by the time blood glucose reached 1 mM. These subjects were completely asymptomatic and 100% neurologically functional.
https://peterattiamd.com/ketosis-advantaged-or-misunderstood...
it is not controversial that the brain can survive long periods of time on principally ketones, but what has not yet been proven (for obvious ethical reasons) is whether or not the brain can sustain itself with absolutely no glucose whatsoever.
again, the ratios are key. i'm not contesting that ketones can be used as the principal fuel source, just that "the important thing is ATP" because the brain needs some glucose.
I find it amusingly absurd how so many people here seem convinced that our primary food source is somehow a poison. People with 0 carbs in their blood are colloquially known as 'dead'.
I wonder if people even know what ketone bodies are... They are a downstream product of glucose processing(also downstream of fats - the inputs are different but the outputs are identical in a few ways), acetyl-coA, stuck together for bloodstream transport with the coenzyme temporarily removed.
Excess protein (in fact, even in the amounts society recognizes as "normal") is bad for you. https://www.youtube.com/watch?v=2R07FL1wVo4
But still, I gave him the benefit of the doubt and sincerely asked him, and ask others here, "Please provide me with studies that show that it's 'horrible for the brain'." I don't mean that to be snarky. I've looked and haven't been able to find the studies. Maybe I've been looking in the wrong places and I would love to read the studies* that show how bad it is.
Towards the end of the conversation with this guy I found it amusing that he stopped chiding me long enough to ask, "So... wait, what is Keto?"
* Peer-reviewed, scientifically rigorous studies only please.
Seriously, I had an accident in March that necessitated a brain operation and left me in the hospital for over a month. The most surprising after-effect is that I can't always predict or recognize the symptoms arising from that.
Was your keto diet the only change in your life? Going from obese to athletic in 6 months probably includes some other good habits like going to gym/physical activity and good sleep etc. So maybe your change in a lifestyle helped you improve you mood and focus, not necessarily the keto diet in particular?
There's literally thousands of articles on it on pubmed.
Paleo humans never ate meat sounds silly, though.