This is not an argument in good faith.
The social ROI on driving is a net benefit, in our current society (95% of us would be dead in a few weeks, if all cars and trucks disappeared tomorrow.) They cause long-term problems, and we absolutely must be working towards a low-carbon future. Do you have a roadmap towards a low-vaping future? I assume not - so I'm not entirely sure your concern for public health is entirely sincere.
It's also been argued to me that prohibition did not have a particularly large impact on overall crime rates, but may have had a positive impact on public health. Depending on which statistics you want to cite, you can very easily make this case. [1]
So, no, it's not at all clear that prohibition was a disaster, and its entirely possible that had we let that experiment run a generation or two, alcohol consumption today would have been much, much lower.
[1] https://www.aeaweb.org/conference/2014/retrieve.php?pdfid=80...