At my job, we have "do you have any questions for us" part as a standard part of every interview -- and my experience shows that most people always have at least one question.
When I used to not have any questions after the interview - I got rejected what felt like a weirdly high amount and definitely a weird tone from the interviewer.
When I started asking questions - the interviewer seemed to have a much more positive outlook on me and my acceptance rate went up.
I've interviewed a lot and there are people you have to ask questions to or else they will reject you.