Having climbed that mountain, I'm currently diving in to industrial automation: not software automation, but both off the shelf and custom robotics and factory equipment providing manufacturing 'unit operations' for working with metals and polymers. It's quite impressive how little integration currently exists between products from different vendors. There is a huge opportunity here for a software-world startup. Competing concerns include safety, reliability, problem detection, automated issue resolution, machine servicing, tool longevity, vendor desire for lock-in, supplier desire for lock-in, noise, dust, finish, speed, logistics, HR, scalability, cost, etc.