Thanks for the thorough evaluation and results! I was aware of colorspacious but I (wrongfully) assumed that it would be the same result as the other simulators (why would someone use ancient literature to make a modern tool...) Will definitely use it in the future instead.
I like your idea of measuring "distances to all other colors" as a litmus test for color confusion issues. It would have been great to see the spread/standard deviation along with the average, in order to see which color was particularly problematic, rather than simply 'weak' (like Twilight).
You're right that under this rubric it's probably not possible to create a colorblind-friendly rainbow map. I was aiming for the colors to be distinguishable, but not 'equally different', which is a much higher bar.
I am also not convinced that even CIECAM02-UCS can give a meaningful answer for 'long distances'. Once hues are different, I think psychologically we give that 'difference' much more weight than the shade. For example I would guess most people would consider Red and Yellow more different than Red and an (equally dE different) darker shade of Red. So surely this would make rainbows even more problematic.
At the end of the day, Turbo was basically designed to steer Jet-lovers to a somewhat better place, so it looks like by your metric it does accomplish that. I agree that making it truly colorblind-optimal was not accomplished, and would require significant changes (if it's even possible).