As I understand it, it’s a range of things. Water and protection from animals, as other mentioned, is a big part of it. But so is growth speed, most trees grow rather slow, but grass, weeds and shrubbery doesn’t. This means that seedlings can lose the struggle for sunlight if you don’t “now the lawn” around them.
There is also quality of the seedlings. The best example is kitchen herbs. If you buy some
rosemary in a pot at you local supermarket, it’ll taste fine. It’ll probably also survive long enough for you to eat it. If you try to plant it in your garden with the intention of keeping rosemary around for years, then there is a good chance it’ll have died within its first month. That’s because supermarket herbs are mass produced in safe environments, where long term survival isn’t valued. You could get lucky, but you’d have a much higher rate of success if you buy your rosemary from a grower who grew them to be planted outside. This is both slower and more expensive though.
Getting 350 million seedlings, often as cheap as you can, is easier with the mass-production approach, and that’s typically what these projects do.