Yes you can:
https://forums.macrumors.com/threads/unsigned-apps-catalyst-...
WASM is the next best thing to an open, yet secure, platform.
So, instead of walled gardens with signed and checked applications (bad). We have to run untrusted and unchecked code of vendors who run code to track your movements around the web and in their applications? (Even worse)
Desktop Linux aside
Maybe we should make Linux an acceptable platform for more people rather than optimizing for proprietary web applications that you don't even own a copy of anymore.