Have you tried using the Blender 2.8 release candidate UI though? As someone with approximately zero artistic skills and minimal 3D background, I was also turned off by Blender's inscrutable UI patterns 10 years ago.
But with the 2.8 RC news on HN last week I recently tried it again and I have to say that now it seems like the UI is pretty decent. Left click select, a move tool that works like every other move tool in paint, a clear hierarchy view with obvious nestable layers - it seems like many of the weird things I remember (like "drag the divider between the viewport and the menu bar down to see a secret option pane") are gone or redesigned now.
Check out https://www.youtube.com/watch?v=jBqYTgaFDxU for some example usage or https://www.youtube.com/watch?v=lPVpg4_POww for a preview of the UI/UX changes.