Sure. But as always. It depends. If you're writing a highly interactive app and your jQuery script starts containing a lot of view state, eventually you'll go mad and probably duplicate a lot of logic on server and client too.
Seeing your app as a function of a data structure/state is then much simpler. Although it will require a bit more thought initially. App = f(s).
Again, it depends. If you're writing static sites and sprinkles will stay sprinkles, jQuery will probably be a solid choice.