Fast forward for low power clients relies on an "iframe only" track as there decoders can't do many x realtime decode. This is not present in modern file based work flows.
Seeks use the same startup/segmentation requirements as video startup.
Thumbnail scrubbing requires a thumbnail track and is not supported by file based workflows at all.
Clip previews on sites load at low resolution/bitrates and can be poped up to "full resolution" via ABR. Doing a preview of 10x 4k streams without abr wouldn't work even on a modern gaming rig.
I'd love to hear how you'd do SSAI on top of a file based workflow.
You could of course build a "file based" implementation that had all of these features, but you would just be rebuilding DASH or HLS.