A tailored suit with a well made dress shirt is literally one of the most comfortable things you can wear. Plus you look really good.
This is as someone who used to weigh around 255 and now weighs around 170.
The more fit you are, the more comfy fitted/tailored apparel tends to be.
If you are atypically shaped due to various fat deposits, tailored clothing becomes more difficult to get just right in order to not pinch/restrict you in all the wrong places.