I can’t think of any of the big founders that were fat alcoholics - bill gates, Steve Jobs, Zuckerberg, bezos? Pretty sure they all work all the time, as in no weekends, get emails at 11 pm every day, at least when they worked.
A) The people you mention were essentially post scarcity long before they were household names.
B) They had substantially more agency in their work than mid and low level workers.
C) No one in their work life is akin to a “boss.” They have customers, advisors, peers, employees, investors, etc - no bosses.
I think arguing that it’s insane to work 80 hour weeks as a dead end test engineer at a large stagnant company is a straw man. Most people have a tenable goal in mind.
And at the end of it I don’t see the majority of them being fat alcoholics.
The early days of ID software. They worked their day jobs and then worked nights/weekends to create their own games.
The early days of eBay when Pierre Omidyar was up all night fixing the site as it crashed.
People at Netscape sleeping under their desks so they didn't waste time driving to/from work.