Many people start their career with 9 to 5 job and keep getting promoted to the CEO level, but they may not have ability and courage (at least in the beginning of their career) to build a new business right from the scratch.
While entrepreneurs/builders are the people who start and build something (or help others to build something) from nothing.
Serial entrepreneurs (and builders) are always on the move - from one project to another as they are not interested in doing the same thing over and over again on daily basis - they get excited to build something from scratch and once it is built they find the right person to run it (or they help others to build it and move on to the next project).
Serial entrepreneurs (and builders) to me are like King-makers, they are not interested in becoming a king them self and run daily operations. They are like a Guru who has many disciples (kings) who achieve success with his/her skills and knowledge. It is well known saying that a Guru is equal to a 1000 libraries - they know which book is for whom, and when and how to use it.