I have an Entourage Edge and it does have a nice big screen, I I know it supports PDF's I use them all the time. Not positive about table of contents support, but I can try that out in a bit.

It does have a lot of issues though. It has two screens, one e-ink, and one LCD. It uses Android 1.6 right now and has no access to the Android Market. The company that makes it has minimal resources and they are really not supportive of developers. The LCD screen is resistive touch and its responsiveness isn't great. You can get a very long time on a charge if you make sure to turn the LCD off while you are reading.It isn't the worlds greatest e-reader, but it might suit your requirements where nothing else does.