On the contrary, stoicism helps you re-attach, especially if reality as perceived with your old mindset has become unbearable. Think of it as a way of viewing things, and less of suppressing anything. Emotions are generated as a reaction to your perception of reality - you will be fed up by the stranger running a red light, but your anger will swing to concern if you learn that they are heading towards an emergency room. Emotions are really just communicators of the reality you perceive. Stoicism might help you adjust your perception where it is just plain wrong. That’s BTW also how cognitive behavioral therapy works, just with the aid of a professional.

I‘m not sure what you mean with Default Mode Network inhibition. CBD is a cannabinoid, and those are present in all mammal bodies - it’s just an aid for faster repair, especially nerves and brain. You might find your brain working better and clearer, because it regenerates faster.