On one level, the white notes are the notes of the C major scale, and the black notes are the semitones which are left over. Why not put all the semitones in one row? That would be much harder to play. Why split it into "C major" and "leftovers"? A bunch of semi-arbitrary decisions made by early harpsichord manufacturers, I guess, which happen to make the instrument easier to play than most alternatives.
If you're looking for an explanation of why the notes of the major scale sound good together whereas most alternative modes sound weird, that's a more difficult question.