3.5 years ago my cofounder were working on what was actually becoming an okay telecom referral business at the YC Fellowship, but my cofounder and I weren't happy. Pretty much every partner there enthusiastically told us that we should definitely consider doing our totally insane idea to try and bring modernized commercial agriculture to smallholder farmers in subsaharan Africa.
We started our moonshot and it's still growing. I think the only people who really believed in us were us and my parents and a couple YC partners, and a couple people at Accion Venture Labs. That was all we needed though.
By the way, I still think our company is a moonshot. Starting a moonshot company is stressful, it's foolish, it's a thousand mistakes to crawl out of, and by far the most rewarding professional decision I've ever made. Any moonshot worth taking will have a real shot at changing the course of human history, and I'm much happier to have a 0.5% chance of ending hunger then to have a 30% chance of a medium amount of wealth.