After ~20 years of using Debian, I switched my desktop PC to OpenBSD about a year ago due to concerns about the direction Linux has taken (eg. systemd).
It was easier to set up the kind of minimalist desktop I like than on Debian, where I have to change a lot of defaults (eg. switching to sysvinit). The package manager is great, and there are ~10k packages available for 6.4. I'm now looking at switching my server to OpenBSD. I'm keeping some dedicated audio workstations on Linux for now (need the raw performance and drivers), but my impression of OpenBSD so far has been very good.
OpenBSD caveats: Video and audio can be a little glitchy. Releases are only supported for one year. ABI can change between releases. There's no filesystem journal. The only non-BSD filestems supported are msdos and ext2fs (and read/write speeds on those are slow).