I've noticed people can be offended when you refer to them by their adjectives. E.g. "blacks" instead of "black people", "autists" vs "autistic people".
The other removes the emphasis on them being people and is pretty depersonalizing.
As you can imagine, it's much worse when it's a historically marginalized group--as an example, fewer people will care if you say "blondes" vs. "blonde-haired people".
Though this thread has been fascinating.