Python sacrifices so much in the way of efficiency, safety, and maintainability that it's hard to justify the wins in expressiveness. Easily checked errors that should have never made it to production manifest at runtime even after rigorous testing. Increasing performance requires moving to asyncio which drastically reduces readability and limits the code reuse from non-async libraries. Eventually code bases grow so large mypy becomes a must, and we have to contend with interfacing untyped libraries and refactoring all of our existing code with annotations.
Python has its place, but in line with how scary modern software practices are to me, it's crazy that Python has become such a mainstay in production software.