Randomized controlled trials are better, of course.
Randomized controlled trials are better, of course.
Even if you think epidemiological methods are sound, at best they can only generate hypotheses that then need to be tested in clinical trials. Instead, these hypotheses are often prematurely trumpeted to the public as implicit fact in the form of media headlines, dietary guidelines, and well-placed commission reports like this one.
Tragically, more than 80%(3) of these guesses are later proved wrong in clinical trials. With a failure rate this high, nutrition epidemiologists would be better off flipping a coin to decide which foods cause human disease.
(1) https://www.frontiersin.org/articles/10.3389/fnut.2018.00105... (2) https://jamanetwork.com/journals/jama/fullarticle/2698337 (3) https://rss.onlinelibrary.wiley.com/doi/full/10.1111/j.1740-...
Ref: https://www.psychologytoday.com/us/blog/diagnosis-diet/20190...