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Comment by eternalny1 | Hacker News Reader

I have some experience with Ketamine ... the one I can share is when the hospital administered it via IV to put my dislocated shoulder back in place.

It was wild and would certainly NOT be my choice for a sedative in that situation. It hit fast and at first I felt high, doctors faces started to "melt", then a huge black abyss was in front of me and I felt like I was falling head first into it.

I started yelling "no, no!" because it was a very uncomfortable feeling.

Then as I was coming to the entire room was warped, with echoing voices and laughter.

I'll pass on that, not sure how that would help with depression. It would have to be a VERY small dose.

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According to what I can find they were using a dosage of 0.5 mg per kg in this study, but dosages can be as high as 1 to 4.5 mg/kg when used as an anesthetic.

I had the same dose for the same reason, it was very disturbing. Apparently the doctor said it was normal for patients to scream that much.

In a clinic environment they wouldnt be putting ur arm back :) . U would be in a calm environment with nice music and blind folds

Some follow a low dose of around 30-35mg and some go up to 150mg which I found to be life changing

In a situation like that where you're in pain and anxious to start with, and are not prepared for what's going to happen, I can imagine it would be pretty horrible. I was in a comfortable situation and well-prepared when I got my first IV, and there were still a couple of brief, scary moments in the experience. And as someone else said, you probably got a much bigger dose, putting you deep into k-hole territory, if not actually knocking you out. When used for therapy, that kind of dose is usually reserved for those with chronic pain or other conditions, not depression or suicidal ideation.

I don't think they would have given you the same dose if it was to treat depression. By the sounds of your trip, you had way more than the standard dose (even by recreational standards).

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