Hard to believe we are 129 comments into this and there are zero mentions of 'borg' in the comment threads ...
For those that don't know, borg is a backup utility[1] that has been called the "holy grail of backups"[2].
It takes your plaintext files and directories, chops them into gpg-encrypted chunks with encrypted, random filenames, and will upload (and maintain) them, with an efficient, changes-only update, to any SFTP/SSH capable server.
My understanding is that the reason people are using borg instead of duplicity is that duplicity forces you to re-upload your entire backup set every month or two or three, depending on how often you update ... and borg just lets you keep updating the remote copy forever.