Some people have written about AppImages, this also applies to FlatPak and similar techs too. Isolating anything more complicated than a command line tool is the way forward and the tech exists. Not using isolation this way is a recipe for pain, whether it be on the desktop or the server (or the phone).
It depends how the plugins are loaded - it'd be great if they could use sockets so that AppImages were viable. No idea myself, though.