I am surprised no one has mentioned Pyramid and SQLAlchemy yet. SQLAlchemy is by far the most complete ORM/Query-Builder I have used (yes, I have tried out Rails, Django and Hibernate).

Also Pyramid's traversal routing is awesome to build REST-applications and ACL authorization.

What ever stack you decide on, I recommend to stay away from too much magic as it complicates debugging and understanding the framework completely (Hibernate, Laravel). If a framework needs to dynamically generate proxy classes, either the framework has a bad approach or the language is not the right choice for the approach.