I go out on sightseeing trips now and then, and very predictably at about 10 days I'm itching to go home and get back to work.
I did go on a 3 day cruise once. By the third day I was bored out of my mind. I tried to get a tour of the engine room but the crew wasn't having any of that. I also annoyed the crew by complaining that they'd changed course to avoid a storm.