But exercise does: https://www.news-medical.net/news/20160324/Exercise-slows-do...
>> Our results suggest that moderate to intense exercise may help older people delay aging of the brain, but more research from randomized clinical trials comparing exercise programs to more sedentary activity is needed to confirm these results.
Are you homo or heterozygous for E4?
the receptors responsible for escorting insulin across the blood-brain barrier can become resistant to insulin, restricting the amount of insulin allowed into the brain. While most brain cells don’t require insulin in order to absorb glucose, they do require insulin in order to process glucose. [..] Despite swimming in a sea of glucose, brain cells in people with insulin resistance literally begin starving to death. [..] Which brain cells go first? The hippocampus is the brain's memory center. Hippocampal cells require so much energy to do their important work that they often need extra boosts of glucose. While insulin is not required to let a normal amount of glucose into the hippocampus, these special glucose surges do require insulin, making the hippocampus particularly sensitive to insulin deficits. This explains why declining memory is one of the earliest signs of Alzheimer’s, despite the fact that Alzheimer’s Disease eventually destroys the whole brain.
researchers have discovered that Alzheimer’s Disease is preceded by DECADES of gradually worsening glucose hypometabolism.
2012 study showed that a low-carbohydrate high-fat diet improved memory in people with “Mild Cognitive Impairment” (Pre-Alzheimer’s Disease) in only six weeks.
https://coconutketones.com/ - Dr Mary Newport's work on coconut oil and low carb diet with her husband with early onset alzheimers and dementia, intended to provide an alternative ketone source of fuel for the brain instead of glucose.
Grain and sugar elimination: that’s huge, because it’s anti-inflammatory. A big driver of cognitive decline and dementia is inflammation. By going grain-free sugar-free we drop inflammation dramatically. If you were to track inflammatory measures like C-reactive protein or interleukin-6 or tumor necrosis factor (TNFα) or other measures, you would see them drop precipitously, as inflammation recedes, and risk for Alzheimer’s with it. - https://www.wheatbellyblog.com/2017/11/preventing-cognitive-...
I wonder how much this has to do with the relative uptake of carbohydrate sources and in particular refined sugars (namely fructose) in the typical diet. It seems the more that we learn, the less good refined vegetable oils and the level of fructose intake in people's diets is. I'm not convinced the amount of refined grains people eat is particularly good either.
However is seems that sugar (fructose specifically) and refined oils (linoleic acid specifically) are particularly bad in the increased quantities since the early 1900's.
I did a google search and found a bunch of resources, but I though some ppl here may have actual experiences to share.
Calories do count, but hormonal response is a primary factor.
Edit: it's worth noting that a certain amount of fat is absolutely needed and is sating in and of itself.
Personally, I don't think the amount of fat you get (in terms of calories) should be lower than the amount of protein you consume, and should come from better sources excluding refined vegetable oils (which are everywhere). My opinion on this is somewhat based on the relative amounts of fat to protein in sources where you get protein naturally. I also feel that not getting enough fat is a big factor in gallbladder dysfunction and stones.
A lot of my opinions are just from common sense, observation and a lot of reading on relatively recent diet and nutrition shifts, and feel levels/extremes can vary based on general health, metabolic syndrome indicators and outright diabetic progression.