I think you're going about it all wrong. If a job is listed on a job aggregator website, I assume its garbage. Here's what I would do. Pick n (5? 10? 15?) companies you'd like to work for. Then research them all until you know everything about the company. Find out what their founder, CEO, designers are complaining about. Look over their website and find three or four problems.
E-mail them saying, "I'm interested in your company, and I'd love to work for you. In the mean time you can check me out here, here and here. I found x, y, z. Here's how I'd fix them. If you'd like to talk further I'm available on Skype, email, and my phone number is x. Call anytime."