We do not know that and it may very well be false.
Yeast was known of and observed for thousands of years, but was not discovered to be life until the 1800s. The signs of life were there, but were not recognized.
It is just our human bias to envision complexity as only occurring on earth-like planets, on human-like time and size scales, communicating over the EM spectrum, formed of baryonic matter...
We don't ask what Great Filter prevents the aliens from speaking English. But we might if English was the only language known on Earth. What languages other than DNA are spoken in the universe?