I wouldn't expect a thoughtful reply, tobyhinloopen seems to be trolling all over the comments here.
All over? I placed like 2-3 comments that can be considered “trolling”
Pretty much everything made by Adobe and Microsoft (but I can sort of live without the ones from Microsoft). Honestly, if Adobe made a Linux distribution as part of Creative Suite (which I would think wouldn't even be hard for them to port to Linux) I bet they could make a strong running taking over the desktop operating system market.
Chief Architect.
Cubase.
Photoshop, InDesign.
Games that don’t work in Wine (eg Fortnite)
Epic, Allscripts, Cerner frontends.
I'd like to see a way of installing applications that isn't needlessly restrictive. Something like AppImage, only actually used.