I feel it all the time. Especially in India where high standard living goes hand to hand with super-poor living.
You really need to be on the ground to help these folks. There are NGOs and social organizations doing this on the ground. I think online tech space can either assist this (for example a web app for an NGO that collects clothes) or a startup that tracks/rates various NGOs and monitors their funding/spending etc.
I am no expert. My few quick thoughts.
As for direct effect of tech venture on these problems, the effect is only of a trickle-down magnitude.