I long ago lost interest in PC gaming, both from the lack of cross-platform compatibility, and due to the fact that a great graphics card alone easily costs as much as a console these days.
I've never played a WINE-wrapped video game or application that did not feel like a half-baked version of it's native application. It's usually things like fonts and strange aliasing that are a complete and dead giveaway. Small aesthetic issues like that completely ruin an otherwise immersive experience for me.
I'm glad WINE exists, but I honestly sort of wish they'd just stick to supporting applications more, and pretty much just forget the gaming side. It's never going to get to an equivalent level, because Windows' gaming technology keeps moving forward.
Two people start running a race. One of them starts when the gun fires. The other one sits and waits, decides it wants to follow the first runner every step of the way, and starts several minutes (or years, in this metaphor) behind the first.
Even if this second runner (WINE) could run as fast as the first (Windows), it would never catch up. And that's assuming it could run as fast as a multi-billion-dollar company.
WINE can, simply, never reach a point of compatibility that even most major console emulators have. Because, unlike consoles, Windows keeps on moving.
Let's face it. None of us are running *nix or MacOS for the sake of gaming. If you want to run a desktop OS for gaming, there is one. Yes, it's not free, but neither are games. Windows is, at this point, just part of the initial cost of PC gaming, just like a couple extra controllers might be for a console.