Incidentally (and speaking of breaking compatibility), MSFT is working on a brand new kernel and operating environment (Midori) which does have ARM as a target. But this is an incubation project with no guaranteed release, though it's a very serious effort.
Source: http://en.wikipedia.org/wiki/Endianness#Bi-endian_hardware
Apple and Android have shown that you can build a mainstream platform ecosystem from nothing in 2-3 years, so who needs Windows compatibility?
iOS is based on OS-X, which is based on NeXT, which is based on BSD (~40 years of work)
Android is based on Linux (so ~20 years of work)
All a new platforms needs is a great webbrowser (which these days seems to mean "port webkit") and it's instantly viable.