In email the From: address rarely delivers the mail. From: and To: are the ones that you see in your mail client and correspond to the addresses on the letter within.
For example here are some headers from some spam I received:
From: "Jeremy Adamson" <jeremyadamson@illusion24.com>
Reply-To: "Jeremy Adamson" <jeremyadamsonr@yahoo.com>
From: is what I see in my client and Reply-To: is where a reply would go to.
This one is much better, note how I'm BCCd and To: is complete bollocks:
Reply-To: dr.ahmed.faruk@outlook.com
From: Dr Faruk Ahmed <dr.faruk.ahmed1@gmail.com>
Subject: MANAGER AUDIT AND ACCOUNT DEPT
To: undisclosed-recipients:;
BCC: <gerdesj@blueloop.net>
Return-Path: dr.faruk.ahmed1@gmail.com
Given that Reply-To and Return-Path are in different domains, where would a reply go to?