What kind of stack are you currently developing in?
The backend is written in Node with PostgreSQL as the database. Since it's a large dataset (terabytes), we rely quite a bit on PostgreSQL 10's partitioning feature for our larger tables: https://www.postgresql.org/docs/10/static/ddl-partitioning.h...
The machine learning code is written in Python, using Keras, TensorFlow, Pandas, scikit-learn, statsmodels. Our AAAI-2018 paper has a bit more info on how DeepHeart (our deep neural network) works. We also do feature engineering and traditional machine learning models when appropriate: https://www.aaai.org/ocs/index.php/AAAI/AAAI18/paper/view/16...