It is said that at the beginning of the 20. century many physicists thought that there wasn't that much more to discover and that most of the theories had been worked out already. There were a few areas where "weird" phenomena were observed (notably in electrodynamics and atom theory) but many people were confident that these would eventually be resolved with the existing theories. Fast forward 20 years and two completely new fields of physics (quantum mechanics and relativity) were discovered.
Personally I still think that we've just scratched the surface of the laws of the universe and it's not impossible that we'll have another wave of theories that will make our current understanding of physics seem hopelessly outdated by the end of the century. And in fact there are some areas where "weird" stuff seems to happen, dark energy or dark matter is a good example for this. I'd be really disappointed if we already discovered everything there is as well in terms of the laws of physics, I mean how boring would that be?