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Comment by Fnoord | Hacker News Reader

What about the rebound effect ("tuesday dip")?

from what I understand, in a medical setting, those treated with MDMA are not / have not been regular users.

New recreational users very often do not get a prolonged comedown / tuesday blues / suicide wednesday. Which is more indicative of heavier user, multiple doses, staying up all night, taking over drugs (including alcohol).

In a controlled setting, with a correct one time dose, in a clinical environment, not running around like a loon, sleeping and eating well, in one off sessions, the mid week comedown can be mitagated away

As senorjazz mentioned, I wonder how much of the really bad recoveries are due to taking too much, mixing it with other drugs, staying up super late, etc?

I only did it a handful of times, a long time ago, but if I took a reasonable amount and just had a chill night on the beach with friends, the recovery wasn’t so bad. One day of feeling tired/down, but similar intensity to a moderate hangover.

MDMA, when I used it, was always combined with dancing or walking or physical activity. I also always had a coming down which had a bottom peak a few days after (the infamous Tuesday dip). With psilocybin I had not much of a coming down, at worst a headache the day after. With MDMA though, the coming down additionally had my mood being down as well. I become agitated and inward, very much in contrast to the peak and moderate upper effect (there are some movies which portrait this, such as the movie Human Traffic [1]). Then again, this is anecdotal, and I am very sensitive to drugs in general, especially the contrasts (alcohol, beer makes me often tired, MDMA, SSRIs, amphetamine). The reason for that might very well be related to ASD, I do not know for sure though. I just know that I do have ASD. But because I have ASD, my anecdotal experience isn't typical in this case. However the Tuesday dip is widely known among MDMA users.

[1] https://en.wikipedia.org/wiki/Human_Traffic

so known so people use additional things to avoid it. personally i'm also very affected by the comedown. whatever makes everything feel great comes as just a big price in the other direction. this is also the reason that perhaps stuff like depression might make it feel even worse.. and only solution would seem is to do it again more regular.

i didn't experience this. the next day, i was mostly just tired from not having slept. then again, it was a one-off thing. might be harder for regular users.

Exactly. :)

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