This article really barely touches on the issue, even with regard to earlier influential architectures by DEC alone (plenty of others contributed as well, though in this regard the most influential were DEC, Intel and IBM in no particular order). It also ignores Gordon Bell, possibly the inventor of the ISA as an idea with his profound design choices in the early DEC architectures.

The most important machines to DEC were PDP-1->PDP-6->PDP-10->DEc-20", PDP8, and PDP-11->VAX, and from an ISA perspective the -10 and -11/Vax sequences had pervasive influence until today.

The 36-bit PDP6 architecture (unfairly called a "dead end" by another poster on this discussion) was highly influential: it was highly orthogonal and what we would consider today almost RISC, but was easy to program in both assembly and with a compiler. This is the architecture that gave us the Internet, Lisp machines, the bitblt instruction (ever used a bitmapped display?) and other technologies that led to today. The PDP-11 gave us C[+] -- there's a little PDP-11-like machine in every C and C++ compiler, and pretty much every other CPU-targeting compiler these days, and as a result, almost every modern ISA looks like a PDP-11 if you squint a little.

(The article also ignores what a barn burner Alpha was. Its biggest misfortune was to be born at the wrong time into a family that had fallen on hard times).