Off the top of my head:
- banking crisis and the complete lack of judicial redress
- the WMD lies for the second Iraq war and the lack of judicial response for the perrpetrators
- tobacco/health disinformation campaigns and the lack of judicial response
- widening income disparity and the lack of political will/power to reverse it
- climate change disinformation and the lack of any meaningful political action
- systematic tax dodging via tax havens and the lack of political response
- militarization of police
In general, the fact that for-profit companies consistently succeed in undermining the ability for society to correct them (by "financing" politicians, by disinforming the public, or by simply cheating around the regulations).
One of the reasons that the GMO and anti-vax discussions can fester on is because organizations like the EPA and the FDA are viewed as completely corrupt; the authorities simply have no credible authority left.