TL;DR: I believe in “work smarter, not harder,” but most people I know/knew believe in the opposite.
However, I think that there is a potential problem in some arbitrage. Arbitrage depends on information asymmetry, and I think that labouring to perpetuate information asymmetry is unethical. (I would say that failing to eliminate the asymmetry when you could easily do so is a grey area.) So if you are an arbitrageur in an area where the market is trying to eliminate your advantage, you have a moral hazard.
This perspective was driven by utilitarian ethics, of course.
The business model of the thrift store requires treating the books as commodities ("all hardcovers $2/ea", etc.), as they don't have the volume to invest time in research. The business model of the used book seller requires knowledge, amortizing the cost of researching each book over a global (or at least national) customer base.
Adam Smith would find this a wonderful example of division of labor.