>0.5g or 500mcg
I hope you mean 0.5 mg not 0.5g because that would be a very big dose!
I hope you mean 0.5 mg not 0.5g because that would be a very big dose!
> There have been few studies on sighted young people. One finds that 1 mg works but 0.3 mg doesn’t; this study is an outlier. Another study on 25yo found both to work equally. Another study on 22-24yo found that 0.3 mg worked better than 1.0. UpToDate and Mayo Clinic suggests using at most .5mg. John Hopkins’ experts almost agree: they say “less is more” but recommend 1-3 mg.
I wonder if I should actually start cutting my pills in 20ths now... The author goes on to say he personally thinks that .3mg is a good amount and anything beyond 1mg is too much.
Edit: Sorry for the edits, I read the article after I made my comment, then figured I'd share their answer since I asked the question myself.
That's one of the key points of the article:
> “But my local drugstore sells 10 mg pills! When I asked if they had anything lower, they looked through their stockroom and were eventually able to find 3 mg pills! And you’re saying the correct dose is a third of a milligram?!”
> Yes. Most existing melatonin tablets are around ten to thirty times the correct dose.
Melatonin has a U shaped dose curve so you either need a tiny bit or a whole lot to be effective.
500ug leaves me groggy in the morning, 250 is perfect.