I have a Kinesis keyboard and used a Microsoft Natural before that. If I were looking for a replacement keyboard, I would base most of my evaluation on three things:

- Does it separate out the hands? This one does to some extent, but it looks like less than the Microsoft or Kinesis.

- How many keys do you need to press with your pinky? What I like most about the Kinesis is that it moves many keys traditionally pressed with the pinky finger - control, alt, enter, backspace, delete - to under the thumbs. It's much easier to hold the modifiers down with your thumb because the muscle is so much bigger, and it's nicer to hit enter/backspace because you don't have to stretch your finger.

- Does it have mechanical key switches instead of the plastic bubbles? I don't know how good this one's are, but it's noticeably less work to press the switches and requires a constant/predictable amount of force on the Kinesis compared to the Microsoft and others. This really adds up over a day of typing.