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ME cleaner is not claiming to render ME completely ineffective, as far as I remember.

me_cleaner removes most of the ME code (including the HTTP parser listed here) and then causes it to crash after bringing up the system, so it's impossible to communicate with the processor running ME. That's about as good as it gets.

Minimize != Disable.

You can disable the first generation ME

https://libreboot.org/docs/hardware/gm45_remove_me.html

after that it's impossible though.

Is that an official tool supported by intel?

No, it's a reverse engineer by the open source community AFAIK.

But very stable, I am looking to flash my X220 soon for what it's worth.

I did this about a year ago on my X230. Works fine.